Case story database

Search for Successfully Implemented Alternatives

You can use the free text search function to find information in the case story database. Most suitable are: substance name and other substance identifier (EC- and CAS-number). You can refine your search after first entry for sector-, function- and process-categories. The case studies are meant to serve as source of inspiration and ideas for substitution. The alternatives are constantly being developed further. We therefore recommend that you to check in each individual case whether an alternative is suitable for your applications and purposes. If you are aware of any other relevant information that is not mentioned in the current case story, please contact SUBSPORTplus.

In order to utilize information in the best way, please take note of the SUBSPORTplus methodology on case stories!

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Substitution of allergenic preservatives: methylisothiazolinone and methylchloroisothiazolinone

A Ph.D. thesis showed that methylisothiazolinone could be remarkably reduced if it was combined with phenoxyethanol in conservation of cosmetic cream.

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Substitution of glutaraldehyde with a solution of peracetic acid and hydrogen peroxide as a disinfectant of medical equipment.

Glutaraldehyde has previously been used to disinfect heat-sensitive medical equipment in dishwashers. It was found that glutaraldehyde could be substituted with a solution of peroxyacetic acid and hydrogen peroxide.

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Reduction of chlorine for disinfection in swimming pools

Chlorine is used as a disinfectant in swimming pools. Chlorine has the advantage of being effective against a considerable number of microorganisms. When adding free chlorine to swimming pool water, however, a very large number of unwanted chlorinated by-products are formed. Other compounds can be used for disinfection, but they are not as efficient and fast-acting as chlorine. But if e.g. silver compounds are combined with a non-chemical alternative as filtration a good result can be achieved.

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Carbon dioxide as alternative to sterilization using ethylene oxide

Ethylene oxide is a disinfectant used in different sectors such as food industry. It is classified as carcinogen, mutagen and reproductive toxicant of category 1B. It may be substituted by different other less hazardous chemicals or technologies. Carbon dioxide may be used as an effective and less toxic alternative.

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Ultrasound as alternative to biocides in cooling water application

Cooling towers provide a good environment for the development of biofilm, algae and microorganisms. Biocides are used to control this process. Dibromo-nitro-propionamide (DBNPA) (2,2-Dibromo-2-cyanoacetamide) biocidal efficacy was compared to that of an ultrasound technology, used as alternative. Results showed a good performance in the case of the ultrasound device

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Ultra sound system as alternative to sodium hypochlorite for bacteria control in the cooling towers of a university

A university decided to switch to ultrasounds for controlling bacteria in its water cooling towers. The system proved effective and helped to cut costs with the previously used chemical biocide (sodium hypochlorite) but also with substances needed to counterbalance the corrosiveness of the biocide and its alkalinity.

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Eine elektromagnetische Technologie zur Vermeidung von mikrobiologischen und Kalkablagerungen

Eine elektronische Technologie zur Vermeidung von Ablagerungen kann gefährliche Chemikalien ersetzen, die in Wasserenthärtungs- und -aufbereitungsanlagen zur Bekämpfung von Kalkablagerungen und Biofouling eingesetzt werden.

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Electro-magnetic technology for scale and bio fouling control

An electronic deposit control technology can replace hazardous chemicals used to combat scale and bio-fouling in water conditioning and treatment systems.

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The cleaning of old frescoes with a bacterial suspension

This case story presents the use of Pseudomonas stutzeri for the biocleaning of mural paintings, for the purpose of eliminating remains of organic material from old restorations or insoluble saline efflorescence. Traditional techniques used in cleaning involve: solvents, spirits, alkalis, acids and soaps, as well as simple mechanical actions (ex. scraping with a scalpel).

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Substitution eines Desinfektionsmittels in einem Altenheim

Ein Altenheim nutzte ein Desinfektionsmittel, das unter anderem drei endokrine Disruptoren enthielt. Eine der Arbeitskräfte erlitt Reizungen im Hals und Atembeschwerden. Das Antiseptikum wurde durch ein auf Didecyldimethylammoniumchlorid und ethoxylierten Alkoholen basierendes Produkt substituiert. Diese Stoffe haben keine signifikanten Auswirkungen auf die Gesundheit des Menschen.

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