Case story database

Search for Successfully Implemented Alternatives

You can use the free text search function to find information in the case story database. Most suitable are: substance name and other substance identifier (EC- and CAS-number). You can refine your search after first entry for sector-, function- and process-categories. The case studies are meant to serve as source of inspiration and ideas for substitution. The alternatives are constantly being developed further. We therefore recommend that you to check in each individual case whether an alternative is suitable for your applications and purposes. If you are aware of any other relevant information that is not mentioned in the current case story, please contact SUBSPORTplus.

In order to utilize information in the best way, please take note of the SUBSPORTplus methodology on case stories!

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Im nationalen Zentrum für Gesundheitsdaten und Seuchenschutz in Dänemark (SSI) ausgeführte Substitutionen.

SSI hat es geschafft, Borsäure, Ethidiumbromid und Ether durch Essigsäure, einen nicht-mutagenen DNA-Farbstoff und Natriumhydroxid zu substituieren. Derzeit wird an der Bewertung einer Alternative zu Trypanblau in der Zellfärbung gearbeitet.

Substitution von Formaldehyd als Gewebefixiermittel

Formaldehyd ist eine organische Verbindung, die als Gewebefixiermittel in der Mikroskopie und Histologie verwendet wird. Das Formaldehyd wurde durch ein Produkt mit dem gewerblichen Namen Fixall-his substituiert, das Ethanol, Isopropanol und Essigsäure enthält.

Treating head lice naturally

In many schools and nurseries head louse alarm is regularly signalled. The use of chemicals such as malathion, permethrin and lindane is more dangerous for the health care staff and children because of louses."die umweltberatung" Österreich (Austrian Eco Counselling) had collected and tested alternatives.

Substitutions performed at the National Centre for Health Data and Disease Control in Denmark (SSI)

SSI have managed to substitute boric acid, ethidium bromide and ether with acetic acid, a non-mutagenic DNA dye and sodium hydroxide. They are currently working on validation of an alternative to Trypan Blue in cell staining.

Substitution of formaldehyde as a tissue fixative

Formaldehyde is an organic compound used as a tissue fixative for microscopy and histology. Formaldehyde was substituted by a product containing: ethyl alcohol, isopropyl alcohol and acetic acid under the commercial name Fixall-his.

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